Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 1693 |
| PMID | 25967040 |
| Year | 2015 |
| Biomarker | sE-Cadherin |
| Biomarker Basis | Concentration Based |
| Biomolecule | Protein |
| Source | Serum |
| Subjects | Humans |
| Regulation | Downregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathway include: Cell junction organization; CDK-mediated phosphorylation and removal of Cdc6; ERK Signaling; Apoptotic cleavage of cellular proteins; Listeria monocytogenes entry into host cells |
| Experiment | Gleason Upgrade Vs No Gleason Upgrade |
| Type of Biomarker | Prognostic |
| Cohort | 165 PCa patients and 19 controls were chosen for analysis. 85 patients experienced Gleason upgrade |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.03 |
| Method Used | ELISA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |