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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1692
PMID25967040
Year2015
BiomarkersE-Cadherin
Biomarker BasisConcentration Based
BiomoleculeProtein
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathway include: Cell junction organization; CDK-mediated phosphorylation and removal of Cdc6; ERK Signaling; Apoptotic cleavage of cellular proteins; Listeria monocytogenes entry into host cells
ExperimentGleason Pattern 3 Vs 4 Vs 5
Type of BiomarkerPrognostic
Cohort165 PCa patients and 19 controls were chosen for analysis. 38 patients with Gleason pattern 3, 104 with 4, 33 with 5
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.02
Method UsedELISA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA