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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1636
PMID31031850
Year2019
BiomarkerCDKN3
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in prostate cancer tissues compared with HR: 2.451 Pathways include: T cell receptor regulation of apoptosis Biochemical recurrence Vs No Biochemical Recurrence Prognostic 498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis NA NA 0.6493 NA p =0.0002558 1635 NA No NA NA Not validated on independent patient dataset 31031850 2019 KIF2C NA Expression Based mRNA Tissue Humans normal tissues
Odds Ratio/Hazard Ratio/Relative RiskHR: 1.930
Effect on PathwaysPathway include: Golgi-to-ER retrograde transport; Cell Cycle, Mitotic; Mitotic Metaphase and Anaphase; Mitotic Prometaphase; Vesicle-mediated transport
ExperimentBiochemical recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis
SenstivityNA
SpecificityNA
AUC0.702
AccuracyNA
Level Of Significancep < 0.0001
Method UsedNA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA