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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1625
PMID31031850
Year2019
BiomarkerCCNB1
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskHR: 1.464
Effect on PathwaysPathways include: T cell receptor regulation of apoptosis, Cell cycle, Oncostatin M, Chk1/Chk2(Cds1)-mediated inactivation of cyclin B-Cdk1 complex, p53 signaling pathway
ExperimentBiochemical recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis
SenstivityNA
SpecificityNA
AUC0.5977
AccuracyNA
Level Of Significancep=0.0166
Method UsedNA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA