Biomarker ID | 1624 |
PMID | 31031850 |
Year | 2019 |
Biomarker | KIF20A |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in prostate cancer tissues compared with HR: 2.060 Pathways include: Kinesins, Aurora B signaling, Polo-like kinase 1 (PLK1) pathway, M phase pathway, MHC class II antigen presentation Prostate Cancer Vs No Prostate Cancer Diagnostic 498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis NA NA 0.8406 (95% CI: 0.6603-0.8256) NA p < 0.0001 1623 NA No NA NA Not validated on independent patient dataset
31031850 2019 CDK1 NA Expression Based mRNA Tissue Humans normal tissues |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 1.856 |
Effect on Pathways | Pathways include: Signal transduction, Immune system, Signaling by GPCR, Interleukin-2 signaling pathway, Disease |
Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | 498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis |
Senstivity | NA |
Specificity | NA |
AUC | 0.6716 |
Accuracy | NA |
Level Of Significance | p < 0.0001 |
Method Used | NA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |