CTYPE html> ProCanBio | Biomarker Card

Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1624
PMID31031850
Year2019
BiomarkerKIF20A
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in prostate cancer tissues compared with HR: 2.060 Pathways include: Kinesins, Aurora B signaling, Polo-like kinase 1 (PLK1) pathway, M phase pathway, MHC class II antigen presentation Prostate Cancer Vs No Prostate Cancer Diagnostic 498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis NA NA 0.8406 (95% CI: 0.6603-0.8256) NA p < 0.0001 1623 NA No NA NA Not validated on independent patient dataset 31031850 2019 CDK1 NA Expression Based mRNA Tissue Humans normal tissues
Odds Ratio/Hazard Ratio/Relative RiskHR: 1.856
Effect on PathwaysPathways include: Signal transduction, Immune system, Signaling by GPCR, Interleukin-2 signaling pathway, Disease
ExperimentBiochemical recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort498 cases from TCGA-PRAD were analysed along with 52 normal prostate controls were selected for the analysis
SenstivityNA
SpecificityNA
AUC0.6716
AccuracyNA
Level Of Significancep < 0.0001
Method UsedNA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA