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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID162
PMID16618727
Year2006
BiomarkerSMPDL3B (Sphingomyelinase like phosphodiesterase 3B) [SMPDL3B 2030]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-NRK human kinase ARCHS4 coexpression, ROR1 human kinase ARCHS4 coexpression,EPHA1 human kinase ARCHS4 coexpression
ExperimentCancerous Tissue Vs Normal Tissue
Type of BiomarkerDiagnostic
CohortTwo sets of Patients were included in the study. Set 1 included 10 cancerous, and 6 normal tissues. Set 2 included 12 cancerous and 10 normal tissues
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significance2.32E-08
Method UsedRT-PCR and qPCR
ClinicalNo
RemarksBrackets indicate ISOFORMS of the mRNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameSMPDL3B