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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1618
PMID31035590
Year2019
BiomarkerIL4R [SNP: rs3024586; A vs G]
Biomarker BasisMutation Based
BiomoleculeMutation
SourceBlood
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskHR: 2.56 (95% CI: 1.36–4.80)
Effect on PathwaysPathways include: Inflammatory response pathway, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 differentiation pathway, p73 transcription factor network, Hematopoietic cell lineage
ExperimentBiochemical recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort418 patients in the training cohort (80 experiencing Biochemical Recurrence) and 131 patients in the validation cohort (28 experiencing Biochemical Recurrence) were chosen for the study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.003
Method UsedAllele specific PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA