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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1615
PMID31035590
Year2019
BiomarkerFOXO3 [SNP: rs2153960 C Vs T]
Biomarker BasisMutation Based
BiomoleculeMutation
SourceBlood
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskHR: 1.83 (95% CI: 1.27–2.64)
Effect on PathwaysPathways include: Non-small cell lung cancer, PI3K cascade, Kit receptor signaling pathway, Endometrial cancer, Signaling events mediated by stem cell factor receptor (c-Kit)
ExperimentBiochemical recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort418 patients in the training cohort (80 experiencing Biochemical Recurrence) and 131 patients in the validation cohort (28 experiencing Biochemical Recurrence) were chosen for the study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.001
Method UsedAllele specific PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA