Biomarker ID | 1602 |
PMID | 26268996 |
Year | 2015 |
Biomarker | Vascular endothelial growth factor A (VEGF-A) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 1.51 (95% CI: 1.08-2.10) |
Effect on Pathways | Pathway include: Response to elevated platelet cytosolic Ca2+; Development VEGF signaling via VEGFR2 - generic cascades; VEGF Pathway (Qiagen); CDK-mediated phosphorylation and removal of Cdc6; RET signaling |
Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | 535 patients with Prostate Cancer were included in the study out of which 170 experienced Biochemical Recurrence |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.016 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |