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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID16
PMID15067324
Year2004
BiomarkerPPFIA3+COPEB+FOS+JUNB+ZFP36
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationDifferentially Expressed in Recurrent Cancer
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentRecurrence Vs No Recurrence
Type of BiomarkerPrognostic
Cohort21 patients were divided into two subgroups representing prostate cancer with recur- rent (8 patients) and nonrecurrent (13 patients). Validation set consisted of 79 patients with 37 recurrent and 42 non recurrent)
SenstivityRecurrent Cancer Prediction: 75%
SpecificityNon Recurrent Cancer Prediction: 92%
AUCNA
Accuracy86%
Level Of Significancep=0.001
Method UsedRNeasy or Fast-Tract kits
ClinicalNo
RemarksResults shown for Training Set
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NamePPFIA3, KLF6, FOS, JUNB, ZFP36