Biomarker ID | 1598 |
PMID | 26254378 |
Year | 2015 |
Biomarker | −2proPSA |
Biomarker Basis | Concentration Based (ng/L) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa [BPH: 16.0 (3.0-81.0); PCa: 21.0 (4.0-135.0)] |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Benign prostatic hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | 150 patients with Benign Prostatic Hyperplasia and 113 with Prostate cancer were selected for the study |
Senstivity | Cut off 4μg/L: 11%; Cut off 10 μg/L: 79% |
Specificity | Cut off 4μg/L: 96%; Cut off 10 μg/L: 23% |
AUC | 0.62292 |
Accuracy | NA |
Level Of Significance | p = 0.0004 |
Method Used | Chemiluminescence |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |