Biomarker ID | 1596 |
PMID | 26254378 |
Year | 2015 |
Biomarker | %fPSA |
Biomarker Basis | Concentration Based (μg/L) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Downregulated in PCa [BPH: 16.7 (1.8-45.4); PCa:11.7 (4.1-31.7)] |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Benign prostatic hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | 150 patients with Benign Prostatic Hyperplasia and 113 with Prostate cancer were selected for the study |
Senstivity | Cut off 15%: 61%; Cut off 20%: 30% |
Specificity | Cut off 15%: 74%; Cut off 20%: 88% |
AUC | 0.70062 |
Accuracy | NA |
Level Of Significance | p<0.0001 |
Method Used | Chemiluminescence |
Clinical | No |
Remarks | %fPSA = (fPSA/tPSA x 100) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |