| Biomarker ID | 1594 |
| PMID | 25454615 |
| Year | 2015 |
| Biomarker | Kallikrein-related peptidase 2 [hK2]+ intact PSA+ free PSA [fPSA]+total PSA [tPSA] |
| Biomarker Basis | Concentration Based |
| Biomolecule | Protein |
| Source | Blood |
| Subjects | Humans |
| Regulation | Upregulated in GS ≤ 7 |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include (hK2): Galactose metabolism, Fructose and mannose metabolism, Hexose transport, Carbohydrate metabolism, SLC-mediated transmembrane transport |
| Experiment | Gleason Score <7 and Gleason Score ≤7 |
| Type of Biomarker | Prognostic |
| Cohort | 542 patients with Negative Biopsy, 239 with Low grade PCa, and 231 with Gleason Score ≥ 7 were chosen for the study |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.82 |
| Accuracy | NA |
| Level Of Significance | p<0.0001 |
| Method Used | NA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |