| Biomarker ID | 1581 |
| PMID | 25274378 |
| Year | 2014 |
| Biomarker | (Intergenic) KLK3–KLK2: [SNP: rs2735839] (AG+AA/GG) |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | OR: 1.85 (95% CI: 1.31–2.61) |
| Effect on Pathways | NA |
| Experiment | Gleason Score 7 (3+4) Vs Gleason Score 7 (4+3) |
| Type of Biomarker | Prognostic |
| Cohort | 1827 men with Prostate cancer were selected for the study. 675 had Gleason Score ≤ 6 and 231 had GS ≥ 8. 921 had GS=7 |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.0005 |
| Method Used | QIAamp DNA extraction Kit (QIAGEN) |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |