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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1577
PMID25274378
Year2014
Biomarker(Intergenic) KLK3–KLK2: [SNP: rs2735839]
Biomarker BasisMutation Based
BiomoleculeMutation
SourceBlood
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskOR: 1.81 (95% CI: 1.23–2.65)
Effect on PathwaysNA
ExperimentGleason Score ≤ 6 Vs Gleason Score ≥ 8
Type of BiomarkerPrognostic
Cohort1827 men with Prostate cancer were selected for the study. 675 had Gleason Score ≤ 6 and 231 had GS ≥ 8. 921 had GS=7
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.002
Method UsedQIAamp DNA extraction Kit (QIAGEN)
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA