| Biomarker ID | 1576 |
| PMID | 25273821 |
| Year | 2014 |
| Biomarker | AKT1 (SNP: rs2494750) |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | HR; 0.45 (95% CI: 0.23-0.90) |
| Effect on Pathways | Pathways include: CD40/CD40L signaling, PIK3C1/AKT pathway, PI3K/PLC/TRK pathway, PI3K/AKT activation, Inactivation of GSK3 by Akt causes accumulation of beta-catenin in alveolar macrophages |
| Experiment | PCa-specific mortality Vs No PCa-specific mortality |
| Type of Biomarker | Prognostic |
| Cohort | 957 patients were taken for this study out of which 98 had PCa Specific death, 782 did not and 77 unknown reason deaths. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.016 |
| Method Used | MassARRAY iPLEX system |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |