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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1573
PMID31059955
Year2019
BiomarkerGlucose Transporter 1 (GLUT1)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
Regulationincreased with decreased DMFS
Odds Ratio/Hazard Ratio/Relative RiskHR: 2.22 (95% CI: 1.02–4.84)
Effect on PathwaysNA
ExperimentDistant Metastasis Free Survival Vs Distant Metastasis Free Survival
Type of BiomarkerPrognostic
Cohortatients entered into a phase 3 randomised controlled trial of patients receiving EBRT (external beam radiotherapy) or EBRT (n=108) + HDR-BTb (n=110) (high-dose-rate brachytherapy boost). 204 samples were available after immunohistochemistry
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 0.045
Method UsedImmunohistochemistry
ClinicalYes
RemarksNA
Clinical Trial NumberISRCTN NO: ISRCTN98241100
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA