| Biomarker ID | 1553 |
| PMID | 25252191 |
| Year | 2014 |
| Biomarker | miR-221 |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in Recurrent Cases (Recurrent Median: 0.25; Control Median: 0.46) |
| Odds Ratio/Hazard Ratio/Relative Risk | HR: 3.21 (95% CI: 1.21 - 8.53) |
| Effect on Pathways | Pathway include: homophilic cell adhesion via plasma membrane adhesion molecules; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; DNA binding; synapse |
| Experiment | Recurrence Vs No Recurrence |
| Type of Biomarker | Prognostic |
| Cohort | 59 cases with Recurrence and 59 controls were used for the study |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Regulation: p=0.0002; Univariate: p=0.02; Multivariate: p=0.05 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |