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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1551
PMID25248617
Year2014
BiomarkerSTEAP2 (Six transmembrane epithelial antigen of the prostate)
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in Low Risk Localised PCa (5.77 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: TGF-beta regulation of extracellular matrix, T cell receptor regulation of apoptosis
ExperimentLow Risk Localised PCa Vs Normal Tissue
Type of BiomarkerDiagnostic
Cohort4 patients with Low Risk PCa, High Risk PCa, 4 Locally Advanced PCa, 5 Metastatic Tumors and 4 Non Cancer controls were analysed for the study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.022
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA