Biomarker ID | 1551 |
PMID | 25248617 |
Year | 2014 |
Biomarker | STEAP2 (Six transmembrane epithelial antigen of the prostate) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Low Risk Localised PCa (5.77 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: TGF-beta regulation of extracellular matrix, T cell receptor regulation of apoptosis |
Experiment | Low Risk Localised PCa Vs Normal Tissue |
Type of Biomarker | Diagnostic |
Cohort | 4 patients with Low Risk PCa, High Risk PCa, 4 Locally Advanced PCa, 5 Metastatic Tumors and 4 Non Cancer controls were analysed for the study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.022 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |