Biomarker ID | 1547 |
PMID | 25248617 |
Year | 2014 |
Biomarker | STEAP2 (Six transmembrane epithelial antigen of the prostate) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Cell Lines |
Subjects | Humans |
Regulation | Upregulated in DU145 and PC3 (28 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: TGF-beta regulation of extracellular matrix, T cell receptor regulation of apoptosis |
Experiment | Cancerous Vs Non Cancerous Cell Lines |
Type of Biomarker | Diagnostic |
Cohort | PNT2 (Normal Prostate epithelial cell line), and Cancerous: DU145 and PC3 were used for this experiment |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | Western Blotting |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Human Patient Cohort |
Technical Name | NA |