Biomarker ID | 1535 |
PMID | 25190021 |
Year | 2014 |
Biomarker | miRNA-221 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa( BPH: 1.2 ± 2.5; PCa: 6.9±4.6) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathway include: homophilic cell adhesion via plasma membrane adhesion molecules; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; DNA binding; synapse |
Experiment | Prostata Cancer Vs Benign prostatic hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | 20 patients were enrolled in the study. 10 of them had Prostate Cancer and 10 had Benign prostatic hyperplasia (BPH) |
Senstivity | 80% |
Specificity | 80% |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.004 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |