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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1535
PMID25190021
Year2014
BiomarkermiRNA-221
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa( BPH: 1.2 ± 2.5; PCa: 6.9±4.6)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathway include: homophilic cell adhesion via plasma membrane adhesion molecules; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; DNA binding; synapse
ExperimentProstata Cancer Vs Benign prostatic hyperplasia
Type of BiomarkerDiagnostic
Cohort20 patients were enrolled in the study. 10 of them had Prostate Cancer and 10 had Benign prostatic hyperplasia (BPH)
Senstivity80%
Specificity80%
AUCNA
AccuracyNA
Level Of Significancep=0.004
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA