| Biomarker ID | 1533 |
| PMID | 25175169 |
| Year | 2014 |
| Biomarker | cytoplasmic-nuclear factor erythroid 2-related factor 2 (c-Nrf-2) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in Malignant Tissue |
| Odds Ratio/Hazard Ratio/Relative Risk | HR: 2.462 (95% CI: 1.162-5.216) |
| Effect on Pathways | NA |
| Experiment | Overall Survival Vs No Survival |
| Type of Biomarker | Prognostic |
| Cohort | 240 patients with Prostate Cancer such that n=154 with GS 2-6, n=7-10 with GS 7-10. n=109 with Biochemical Recurrence (BCR), 131 without BCR; n=221 with Prostate Cancer Survival, n=19 who died of PCa, n= 189 with Overall Survival, n=51 who died |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Univariate: p=0.28; Multivariate: p=0.019 |
| Method Used | Immunohistochemistry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |