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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1526
PMID25174820
Year2014
BiomarkerDeath Receptor 5
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationDownregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathway include: Dimerization of procaspase-8; Apoptosis Modulation and Signaling; PEDF Induced Signaling; DNA Damage Response; TNFR1 Pathway
ExperimentProstate Cancer Vs PIN
Type of BiomarkerDiagnostic
CohortThe 54 cases of PCa were classified according to the Gleason score as follows: 27 low‐grade prostatic carcinoma [Gleason score 2‐5 (LG PCa)] and 27 high‐grade prostatic carcinoma [Gleason score 6‐10 (HG PCa)]
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.001
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA