| Biomarker ID | 1516 |
| PMID | 25156059 |
| Year | 2014 |
| Biomarker | YWHAZ |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Increased expression in patients with PCa specific death |
| Odds Ratio/Hazard Ratio/Relative Risk | Univariate: HR: 4.28 (95% CI: 1.589 - 11.525); Multivariate: HR: 3.516 (95% CI: 1.275–9.699) |
| Effect on Pathways | Pathways include: FoxO family signaling, Pathogenic Escherichia coli infection, LKB1 signaling events, Calcineurin-dependent NFAT signaling role in lymphocytes, PI3K/PLC/TRK pathway |
| Experiment | High Risk vs Low Risk (Survival) |
| Type of Biomarker | Prognostic |
| Cohort | 213 men who underwent radical prostatectomy were selected for analysis |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Univariate: p=0.004; Multivariate: p = 0.015 |
| Method Used | Immunohistochemistry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |