| Biomarker ID | 1513 |
| PMID | 25151013 |
| Year | 2015 |
| Biomarker | Four-kallikrein panel (Kallikrein-related peptidase 2 [hK2]+ intact PSA+ free PSA [fPSA]+total PSA [tPSA]) |
| Biomarker Basis | Concentration Based (ng/mL) |
| Biomolecule | Protein |
| Source | Plasma |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include (hK2): Galactose metabolism, Fructose and mannose metabolism, Hexose transport, Carbohydrate metabolism, SLC-mediated transmembrane transport |
| Experiment | High-grade Prostate cancer |
| Type of Biomarker | Diagnostic |
| Cohort | 531 men with PSA levels between 3 and 15 ng/ml undergoing first-time prostate biopsy were chosen. 271 had Prostate cancer and 231 had Benign Biopsy |
| Senstivity | NA |
| Specificity | NA |
| AUC | 71.8 (95% 66.8-76.7) |
| Accuracy | NA |
| Level Of Significance | p<0.0001 |
| Method Used | NA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |