Biomarker ID | 1490 |
PMID | 25075566 |
Year | 2014 |
Biomarker | Interferon β (IFNβ) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Decreased in patients with Biochemical Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include: Toll-like Receptor Signaling Pathway; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways; Immune response IFN alpha/beta signaling pathway; Measles; Human cytomegalovirus infection |
Experiment | Recurrence Vs No Recurrence |
Type of Biomarker | Prognostic |
Cohort | 118 patients with primary prostate cancer (78 without and 40 with recurrence during the follow-up period) were selected |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.008 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | cutoff point: 170 |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |