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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1490
PMID25075566
Year2014
BiomarkerInterferon β (IFNβ)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationDecreased in patients with Biochemical Recurrence
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include: Toll-like Receptor Signaling Pathway; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways; Immune response IFN alpha/beta signaling pathway; Measles; Human cytomegalovirus infection
ExperimentRecurrence Vs No Recurrence
Type of BiomarkerPrognostic
Cohort118 patients with primary prostate cancer (78 without and 40 with recurrence during the follow-up period) were selected
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.008
Method UsedImmunohistochemistry
ClinicalNo
Remarkscutoff point: 170
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA