Biomarker ID | 1488 |
PMID | 25075250 |
Year | 2014 |
Biomarker | let-7c |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in Patients With Recurrence (No Recurrence : 0.703 ± 0.098; recurrence: 0.963 ± 0.06) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include: regulation of RNA metabolic process; regulation of nucleic acid-templated transcription; regulation of RNA biosynthetic process; RNA biosynthetic process; regulation of transcription, DNA-templated |
Experiment | PSA Recurrence Vs No Recurrence |
Type of Biomarker | Prognostic |
Cohort | 215 samples were chosen for analysis. 204 were malignant and 11 were benign. 36 with Recurrence and 41 without PSA recurrence |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.0266 |
Method Used | In Situ hybridization (ISH) |
Clinical | No |
Remarks | Results for Stromal cell study |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |