| Biomarker ID | 1488 |
| PMID | 25075250 |
| Year | 2014 |
| Biomarker | let-7c |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in Patients With Recurrence (No Recurrence : 0.703 ± 0.098; recurrence: 0.963 ± 0.06) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include: regulation of RNA metabolic process; regulation of nucleic acid-templated transcription; regulation of RNA biosynthetic process; RNA biosynthetic process; regulation of transcription, DNA-templated |
| Experiment | PSA Recurrence Vs No Recurrence |
| Type of Biomarker | Prognostic |
| Cohort | 215 samples were chosen for analysis. 204 were malignant and 11 were benign. 36 with Recurrence and 41 without PSA recurrence |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.0266 |
| Method Used | In Situ hybridization (ISH) |
| Clinical | No |
| Remarks | Results for Stromal cell study |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |