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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1470
PMID25065599
Year2014
BiomarkermiR-135a
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceTissue
SubjectsHumans
RegulationDownregulated in GS ≥ 8
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; Gene expression (Transcription); synapse; nuclear chromatin
ExperimentGlesaon Score ≥ 8 and Gleason Score <8
Type of BiomarkerPrognostic
Cohort56 tumors and pair-matched adjacent normal tissues from prostatectomy were selected
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.01
Method UsedRT–qPCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA