Biomarker ID | 1459 |
PMID | 25032132 |
Year | 2014 |
Biomarker | Vascular Endothelial Growth Factor (VEGF) + Prostate Specific Antigen (PSA) |
Biomarker Basis | Concentration Based (VEGF: pg/mL; PSA: ng/mL) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa: [VEGF+ PSA] |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 35 (95% CI: 6.3-194.2) |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs (Benign prostatic hyperplasia + Healthy Individuals) |
Type of Biomarker | Diagnostic |
Cohort | 47 patients with Prostate Cancer, 57 with Benign prostatic hyperplasia (BPH) and 57 healthy individuals were selected for the study |
Senstivity | 91% |
Specificity | 87% |
AUC | 0.876 |
Accuracy | NA |
Level Of Significance | NA |
Method Used | ELISA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |