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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1457
PMID25009296
Year2014
BiomarkerBrachyury
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationIncreases with increasing Gleason Score
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysBrachyury are clustered in oncogenic-related pathways, namely cell motility, cell- cycle regulation, and cell metabolism
ExperimentGleason Score GS <7 Vs GS = 7 Vs GS >7
Type of BiomarkerPrognostic
CohortThe series included a total of 211 nonneoplastic tissue, 143 high-grade prostate intraepithelial neoplasia (PIN) lesions, and 409 primary prostate carcinomas.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 0.027
Method UsedWestern Blot
ClinicalNo
RemarksValidated in 4 other data stats, found consistent results with 3 of them
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA