Biomarker ID | 1453 |
PMID | 24938534 |
Year | 2014 |
Biomarker | Glutathione (GSH) |
Biomarker Basis | Concentration Based (μmol/mL) |
Biomolecule | Protein |
Source | Blood |
Subjects | Humans |
Regulation | Downregulated after treatment with SeMet for 9 months (0.22 ± 0.07 change from baseline) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Baseline Vs 9 months later after treatment with SeMet |
Type of Biomarker | Predictive |
Cohort | A total of 130 subjects were randomized, of which 69 were included in the analysis. Out of 69 - 18 were allocated to Placebo, 16 were allocted to low dose SY (selenium-enriched yeast), 15 were allocated to high dose SY and 31 to SeMet (selenomethionine) |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | NA |
Clinical | Yes |
Remarks | NA |
Clinical Trial Number | NCT01112449 |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |