| Biomarker ID | 1449 |
| PMID | 24976077 |
| Year | 2014 |
| Biomarker | mir-221 |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Prostate Secretion Samples |
| Subjects | Humans |
| Regulation | Downregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include: homophilic cell adhesion via plasma membrane adhesion molecules; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; DNA binding; synapse |
| Experiment | Prostate Cancer Vs Benign Prostatic Hyperplasia |
| Type of Biomarker | Diagnostic |
| Cohort | Prostate secretion samples (PSS) from 23 PCa and 25 benign prostate hyperplasia (BPH) patients were obtained |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.706 |
| Accuracy | NA |
| Level Of Significance | p=0.03 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | 4 patients from the cohort were selected for microarray analysis to confirm the results |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | mir-221 |