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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1437
PMID24893170
Year2014
BiomarkermiR_19a+ miR_345+ miR_519c_5p
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceTissue
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskOR: [miR_19a: 9.76 (95% CI: 1.47- 64.82)]; [miR_345: 0.002(95% CI: 0.00-0.65]; miR_519c_5p [0.24 (95% CI: 0.18- 3.21)]
Effect on PathwaysNA
ExperimentGleason Score ≥7 or Gleason Score =6
Type of BiomarkerPrognostic
CohortA validation cohort consisted of 25 cases and 35 controls. Gleason score of 7 or higher (case group) and a pathologic Gleason score of 6 (control group).
SenstivityNA
SpecificityNA
AUC0.930 (95% CI: 0.86-1.00)
AccuracyNA
Level Of Significancep<0.05
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA