Biomarker ID | 1437 |
PMID | 24893170 |
Year | 2014 |
Biomarker | miR_19a+ miR_345+ miR_519c_5p |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | OR: [miR_19a: 9.76 (95% CI: 1.47- 64.82)]; [miR_345: 0.002(95% CI: 0.00-0.65]; miR_519c_5p [0.24 (95% CI: 0.18- 3.21)] |
Effect on Pathways | NA |
Experiment | Gleason Score ≥7 or Gleason Score =6 |
Type of Biomarker | Prognostic |
Cohort | A validation cohort consisted of 25 cases and 35 controls. Gleason score of 7 or higher (case group) and a pathologic Gleason score of 6 (control group). |
Senstivity | NA |
Specificity | NA |
AUC | 0.930 (95% CI: 0.86-1.00) |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |