CTYPE html> ProCanBio | Biomarker Card

Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1434
PMID24893170
Year2014
BiomarkermiR-19b
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in Cases
Odds Ratio/Hazard Ratio/Relative RiskOR: 12.67 (95% CI: 2.72-58.98) p=0.001
Effect on PathwaysPathways include: DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; nuclear chromatin; nuclear chromosome; chromatin,
ExperimentGleason Score ≥7 or Gleason Score =6
Type of BiomarkerPrognostic
CohortA validation cohort consisted of 25 cases and 35 controls. Gleason score of 7 or higher (case group) and a pathologic Gleason score of 6 (control group).
SenstivityNA
SpecificityNA
AUC0.86 (95% CI: 0.76-0.96)
AccuracyNA
Level Of Significancep<0.05
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA