Biomarker ID | 1434 |
PMID | 24893170 |
Year | 2014 |
Biomarker | miR-19b |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Cases |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 12.67 (95% CI: 2.72-58.98) p=0.001 |
Effect on Pathways | Pathways include: DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; nuclear chromatin; nuclear chromosome; chromatin, |
Experiment | Gleason Score ≥7 or Gleason Score =6 |
Type of Biomarker | Prognostic |
Cohort | A validation cohort consisted of 25 cases and 35 controls. Gleason score of 7 or higher (case group) and a pathologic Gleason score of 6 (control group). |
Senstivity | NA |
Specificity | NA |
AUC | 0.86 (95% CI: 0.76-0.96) |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |