Biomarker ID | 1433 |
PMID | 24893170 |
Year | 2014 |
Biomarker | miR-19a |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Cases |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 9.22 (95% CI: 2.27 - 37.43) p=0.002 |
Effect on Pathways | Pathways include: DNA-binding transcription factor activity, RNA polymerase II-specific; nuclear chromatin; chromatin; regulation of RNA metabolic process; nuclear chromosome |
Experiment | Gleason Score ≥7 or Gleason Score =6 |
Type of Biomarker | Prognostic |
Cohort | A validation cohort consisted of 25 cases and 35 controls. Gleason score of 7 or higher (case group) and a pathologic Gleason score of 6 (control group). |
Senstivity | NA |
Specificity | NA |
AUC | 0.85 (95% CI: 0.75- 0.95) |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |