| Biomarker ID | 1431 |
| PMID | 24893170 |
| Year | 2014 |
| Biomarker | miR-345 |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in Cases |
| Odds Ratio/Hazard Ratio/Relative Risk | OR: 0.13 (95% CI: 0.03 - 0.47) p=0.003 |
| Effect on Pathways | Pathways include: intracellular signal transduction; transferase activity; synapse; Golgi apparatus; perinuclear region of cytoplasm |
| Experiment | Gleason Score ≥7 or Gleason Score =6 |
| Type of Biomarker | Prognostic |
| Cohort | The discovery cohort consisted of 48 patients with a post-surgical pathologic Gleason score of 7 or higher (case group) and 48 patients with a pathologic Gleason score of 6 (control group). |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.78 (95% CI: 0.68- 0.87) |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |