| Biomarker ID | 1410 |
| PMID | 24740842 |
| Year | 2014 |
| Biomarker | MTRR [SNP: rs9332: CT] |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | HR: Univariate: Cohort 1: [1.74 (95% CI: 1.15–2.64); Cohort 1+2: [1.45 (95% CI: 1.08–1.94)] |
| Effect on Pathways | Pathways include: One-carbon metabolism, Vitamin B12 metabolism, Folate metabolism |
| Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
| Type of Biomarker | Prognostic |
| Cohort | two independent cohorts composed of 320 Asian and 526 Caucasian men with pathologically organ-confined prostate cancer were selected |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Univariate: Cohort 1: p= 0.008 Cohort 1+2: p=0.01 |
| Method Used | MALDI-TOF |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |