| Biomarker ID | 1404 |
| PMID | 24737792 |
| Year | 2014 |
| Biomarker | miR-452 |
| Biomarker Basis | RNA expression |
| Biomolecule | miRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | Cohort 1 : Univariate: HR: 0.64 (95% CI: 0.29-1.37), p-value= 0.247, C-Index= 0.55 |
| Effect on Pathways | Pathways include: cell development; nervous system development; regulation of signaling; DNA-binding transcription factor activity, RNA polymerase II-specific; cell projection organization |
| Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
| Type of Biomarker | Prognostic |
| Cohort | 30 nonmalignant and 30 prostate cancer tissue samples were used for this analysis |
| Senstivity | 95.5% |
| Specificity | 94.3% |
| AUC | 0.98 |
| Accuracy | NA |
| Level Of Significance | p=0.001 |
| Method Used | Training: Microarray; Validation: qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |