| Biomarker ID | 1403 |
| PMID | 24737792 |
| Year | 2014 |
| Biomarker | miR-224 |
| Biomarker Basis | RNA expression |
| Biomolecule | miRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | Cohort 1 : Univariate: HR: 0.59 (95% CI: 0.38-0.91), P-value= 0.018, C-Index= 0.67; Multivariate: HR= 0.83 (95% CI: 0.53-1.30), p-value= 0.405, C-Index= 0.86 |
| Effect on Pathways | Pathways include: nucleoplasm; glutamatergic synapse; chromatin; nuclear chromosome; synapse |
| Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
| Type of Biomarker | Prognostic |
| Cohort | 30 nonmalignant and 30 prostate cancer tissue samples were used for this analysis |
| Senstivity | 95.5% |
| Specificity | 94.3% |
| AUC | 0.98 |
| Accuracy | NA |
| Level Of Significance | p=0.001 |
| Method Used | Training: Microarray; Validation: qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |