| Biomarker ID | 1386 |
| PMID | 24714754 |
| Year | 2014 |
| Biomarker | mir-146a |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Blood |
| Subjects | Humans |
| Regulation | Downregulated in Non Responders (Median NR/median R): 1.4 fold |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include: cellular response to cytokine stimulus; cytokine-mediated signaling pathway; response to cytokine; Regulation of toll-like receptor signaling pathway; Toll-like Receptor Signaling Pathway |
| Experiment | PSA responder Vs Non Responder (Pre Docetaxel levels) |
| Type of Biomarker | Predictive |
| Cohort | micRNAs were profiled in DU145 cell lines and their docetaxel-resistant sublines (DU145Rx) |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.62 (95% CI: 0.51–0.74) |
| Accuracy | NA |
| Level Of Significance | p=0.05 |
| Method Used | qPCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Human Patient Cohort |
| Technical Name | NA |