Biomarker ID | 1385 |
PMID | 24714754 |
Year | 2014 |
Biomarker | mir-200b |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Blood |
Subjects | Humans |
Regulation | Upregulated in Non Responders (Median NR/median R): 2.7 fold |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: MicroRNAs in cancer; Gene expression (Transcription); RNA Polymerase II Transcription; nucleoplasm; DNA binding |
Experiment | PSA responder Vs Non Responder (Pre Docetaxel levels) |
Type of Biomarker | Predictive |
Cohort | micRNAs were profiled in DU145 cell lines and their docetaxel-resistant sublines (DU145Rx) |
Senstivity | NA |
Specificity | NA |
AUC | 0.64 (95% CI: 0.53–0.75) |
Accuracy | NA |
Level Of Significance | p=0.02 |
Method Used | qPCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Human Patient Cohort |
Technical Name | NA |