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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1384
PMID24714754
Year2014
Biomarkermir-200c
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceBlood
SubjectsHumans
RegulationUpregulated in Non Responders (Median NR/median R): 1.6 fold
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: MicroRNAs in cancer; Gene expression (Transcription); nucleoplasm; positive regulation of cellular metabolic process; positive regulation of protein metabolic process
ExperimentPSA responder Vs Non Responder (Pre Docetaxel levels)
Type of BiomarkerPredictive
CohortmicRNAs were profiled in DU145 cell lines and their docetaxel-resistant sublines (DU145Rx)
SenstivityNA
SpecificityNA
AUC0.64 (95% CI: 0.53–0.75)
AccuracyNA
Level Of Significancep=0.02
Method UsedqPCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on Human Patient Cohort
Technical NameNA