| Biomarker ID | 1351 |
| PMID | 24607843 |
| Year | 2014 |
| Biomarker | miR-221 |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulation in high-risk prostate cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | Cohort 2: HR: 0.026 (95% CI: 0.003–0.201) |
| Effect on Pathways | Pathway Include: homophilic cell adhesion via plasma membrane adhesion molecules; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; DNA binding; synapse |
| Experiment | Cancer Related Death Vs No Cancer Related Death |
| Type of Biomarker | Prognostic |
| Cohort | Cohort 1 included 134 patients with 11 cancer related deaths and Cohort 2 included 89 patients with 15 cancer related deaths |
| Senstivity | NA |
| Specificity | NA |
| AUC | Cohort 1: 90.28% (95% CI: 83.95%–96.61%) |
| Accuracy | NA |
| Level Of Significance | p<0.0001 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |