| Biomarker ID | 134 |
| PMID | 17785564 |
| Year | 2007 |
| Biomarker | Fusion Status of TMPRSS2-ERG |
| Biomarker Basis | Expression Based (Fusion Based) |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Fusion of the genes in Positive Biopsy PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include(ERG):- Genes targeted by miRNAs in adipocytes WP1992, VEGFA-VEGFR2 Signaling Pathway WP3888 |
| Experiment | Positive Vs Negative Biopsies for PCa |
| Type of Biomarker | Prognostic |
| Cohort | A total of 78 men with prostate cancer positive biopsies and 30 men with prostate cancer negative biopsies were included in this study. |
| Senstivity | 37% |
| Specificity | 93% |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | NA |
| Method Used | RT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | TMPRSS2, ERG |