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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1323
PMID24477576
Year2014
BiomarkermiR-101
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceSerum
SubjectsHumans
RegulationDownregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include: DNA binding; Gene expression (Transcription); Generic Transcription Pathway; RNA Polymerase II Transcription; DNA-binding transcription factor activity, RNA polymerase II-specific
ExperimentAfrican Americans Vs Caucasian Americans with PCa
Type of BiomarkerDiagnostic
Cohort40 PCa patients (16 Caucasian American) and (24 African Americans) along with 32 controls (20 Caucasian American) and (12 African Americans) were selected for analysis
SenstivityNA
SpecificityNA
AUC0.80 (95% CI: 0.69-0.90)
AccuracyNA
Level Of Significancep= 0.0006
Method UsedqRT-PCR
ClinicalNo
RemarksAlso significantly downregulated when only Caucasian American population is considered alone
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NamemiR-101