Biomarker ID | 132 |
PMID | 17764114 |
Year | 2008 |
Biomarker | PTGS2 |
Biomarker Basis | Concentration Based(ng/ml) |
Biomolecule | Other |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa [(Mean Values) PCa: 85.95; Healthy Individuals: 10.88] |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Selenium pathway, C-Myb transcription factor network,VEGF signaling pathway,Leishmaniasis,Prostaglandin biosynthesis and regulation |
Experiment | Prostate Cancer (PCa) Vs Healthy Individuals |
Type of Biomarker | Diagnostic |
Cohort | Serum of 216 patients was evaluated. 168 having PCA, 5 incidental PCA, 42 Benign Prostatic Hyperplasia and 11 healthy patients. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | P<0.0001 |
Method Used | RT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | PTGS2 |