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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID132
PMID17764114
Year2008
BiomarkerPTGS2
Biomarker BasisConcentration Based(ng/ml)
BiomoleculeOther
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa [(Mean Values) PCa: 85.95; Healthy Individuals: 10.88]
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Selenium pathway, C-Myb transcription factor network,VEGF signaling pathway,Leishmaniasis,Prostaglandin biosynthesis and regulation
ExperimentProstate Cancer (PCa) Vs Healthy Individuals
Type of BiomarkerDiagnostic
CohortSerum of 216 patients was evaluated. 168 having PCA, 5 incidental PCA, 42 Benign Prostatic Hyperplasia and 11 healthy patients.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of SignificanceP<0.0001
Method UsedRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamePTGS2