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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1299
PMID24394557
Year2014
BiomarkerCTGF
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskHR: 1.15 (95% CI: 1.02–1.29)
Effect on PathwaysPathways include: YAP1- and WWTR1 (TAZ)-stimulated gene expression, Alpha-M beta-2 integrin signaling, RAGE pathway, Lipid metabolism regulation by peroxisome proliferator-activated receptor alpha (PPAR-alpha), Fatty acid, triacylglycerol, and ketone body metabolism
ExperimentPCa Specific Survival Vs No PCa Specific Survival
Type of BiomarkerPrognostic
Cohort189 patients from Swedish Cohort were selected for analysis. Survival information was available for 185 patients. 22 are alive, 98 died due to prostate cancer and 65 died due to other causes.100 samples were available for the analysis of this gene
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.023
Method UsedNA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameCTGF