Biomarker ID | 1289 |
PMID | 24394557 |
Year | 2014 |
Biomarker | WNT5B |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 1.14 (95% CI: 1.04–1.25) |
Effect on Pathways | Pathways inlcude: Basal cell carcinoma, Hedgehog signaling pathway, Wnt/calcium/cyclic GMP pathway, ATM-dependent DNA damage response, Wnt signaling pathway and pluripotency |
Experiment | Overall Survival Vs No Survival |
Type of Biomarker | Prognostic |
Cohort | 189 patients from Swedish Cohort were selected for analysis. Survival information was available for 185 patients. 22 are alive, 98 died due to prostate cancer and 65 died due to other causes. 89 samples were available for the analysis of this gene |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.004 |
Method Used | NA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | WNT5B |