Biomarker ID | 128 |
PMID | 16614113 |
Year | 2006 |
Biomarker | Macrophage Inhibitory Cytokine-1 (MIC-1) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-TAp63 pathway,p73 transcription factor network,p53 signaling pathway, BDNF signaling pathway |
Experiment | Benign Prostate Vs Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | 247 patients who underwent radical prostatectomy having benign, low-grade prostatic intraepithelial neoplasia (PIN), high- grade PIN (HGPIN), and prostate cancer tissue werw taken into examination |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.0001 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | GDF15 |