| Biomarker ID | 1273 |
| PMID | 24371517 |
| Year | 2013 |
| Biomarker | Integrin β1 [ITGB1] |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Urine |
| Subjects | Humans |
| Regulation | Upregulated in Metastatic Prostate Cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include: Mammalian calpain regulation of cell motility, Integrin family cell surface interactions, Alpha-9 beta-1 integrin pathway, Reelin signaling pathway, Syndecan 2 pathway |
| Experiment | Metastasis Vs Prostate Cancer and BPH |
| Type of Biomarker | Diagnostic |
| Cohort | Patients with BPH (n=5), PCa (n=5) and metastatic PCa (n=3) were selected for evaluation of protein expression in the exosomes |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.01 |
| Method Used | Western Blotting |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Human Patient Cohort |
| Technical Name | ITGB1 |